Alexander Fleming

Alexander Fleming was a scientist who was working on staphylococci. These are the germs that make wounds go septic. Whilst cleaning the culture dishes one day he saw a mould growing on one of the plates. This in itself was not unusual, but on this occasion there were no germs growing around the growth. Curious as to what caused the germs to stop growing, and eager to find out what the mould was, Fleming grew more of it and experimented. He found that the mould acted against anthrax and diphtheria without creating any harmful side effects. This was the first occasion that an antibiotic drug had been developed (an antibiotic is something naturally produced by living organisms, rather than being a chemical compound). The new drug was a member of the penicillin notatum family, known popularly as penicillin.

Fleming however did little with his discovery. It wasn't until 1935 when researchers Florey and Chain at Oxford University saw Fleming's research papers that the drug was developed further.

The fight against infectious disease: pages within this unit

What is an Infectious Disease? A Glossary of Infectious Diseases, Edward Jenner, Louis Pasteur, Robert Koch, Vaccination, The Development of Drugs, Paul Ehrlich, Gerhard Domagk, Alexander Fleming, Howard Florey and Ernst Chain, The importance of Penicillin, Factors affecting the development of drugs and treatments.

Activities within the Unit

Glossary vocabulary test	This activity checks your knowledge of infectious disease
Drag and Drop game	Do you know who developed each form of medicine?
Breakthrough against Infectious Disease	Use the information in this unit to answer a detailed question, then see how it compares with a suggested response. Ideal revision tool.

Recommended textbooks and revision guides

Textbooks	Revision Guides

In this unit:

Recommended Resources

Medicinethroughtime.co.uk - new site. Including Blog and use of twitter for free text / IM revision tips.

SchoolsHistory.org.uk highly recommends these sites:

Schoolhistory.co.uk - fantastic range of interactive games, revision materials and links.
ActiveHistory.co.uk - outstanding use of ICT to engage pupils.
Thinkinghistory.co.uk - a brilliant range of learning activities from Ian Dawson
JohnDClare.net - simply the best for Modern World GCSE students
History.org.uk - resources and CPD materials from the Historical Association.
Historyboxes.com - make your lessons 'real' with artefacts and living history provided by experts
Schoolshistory.com - same author as this site, just put together in a slightly different way!